COPYRIGHT STATEMENT
This document is a textbook and may be used in its entirety or excerpted for training and reference purposes.
Any other purpose that is deviant or used for unfair business purposes is strictly prohibited.
INTRODUCTION
The Veterinary Pharmacology textbook is compiled for the intermediate training program of veterinary husbandry. The textbook includes knowledge about the effects of drugs and the therapeutic applications of drugs used in veterinary medicine, helping learners have an overview of drugs used to treat animals, applying the knowledge about the effects and therapeutic applications of drugs as a basis for working after graduation.
The course consists of 4 chapters:
Chapter 1. General information about veterinary medicine Chapter 2. Antibiotics and Sulfamides
Chapter 3: Disinfectants and antiparasitics Chapter 4: Gastrointestinal drugs and supplements
To complete this course, we have received guidance and direction from the Board of Directors of the Northeast College of Agriculture and Forestry; Training Department; Guidance Documents from the Ministry of Labor, Invalids and Social Affairs. The cooperation and assistance of teachers in the veterinary department, the contributions of technical staff of related units. We would like to thank the scientists, technical staff, teachers who have contributed many valuable ideas, creating favorable conditions for the completion of this course.
The textbook is the basis for teachers to prepare lectures for teaching, and is a research and study document for students studying Veterinary Animal Husbandry and Veterinary Medicine. The information in the textbook is valuable in guiding teachers to design and organize lessons in a reasonable manner. Teachers can apply it appropriately to actual conditions and contexts in the teaching process.
During the compilation process, mistakes are inevitable. We hope to receive comments from scientists, technical staff, and colleagues to improve the textbook.
Quang Ninh, December 20, 2020
Participate in editing
1. Mai Thi Thanh Nga (editor-in-chief)
2. Mai Anh Tung
3. Hoang Thi Ngoc Lan
INDEX
1 | |
INTRODUCTION | 2 |
CHAPTER I: GENERAL INFORMATION ABOUT VETERINARY MEDICINE | 10 |
1.1. Concept and origin of veterinary medicine | 12 |
1.1.1. Concept of medicine | 12 |
1.1.2. Origin of the drug | 12 |
1.1.2.1. Natural origin | 12 |
1.1.2.2. Artificial origin | 12 |
1.1.3. Distinguish between drugs, food and poisons | 12 |
2.2. Effects of the drug | 13 |
2.2.1. Local effects and systemic effects | 13 |
1.3.2. Main effects and side effects | 13 |
1.2.3. Reflex effect | 15 |
1.2.4. Remote control effect | 15 |
1.2.5. Selective and specific effects | ---15 |
1.2.6. Direct and indirect effects | 16 |
1.2.7. Reversible and irreversible effects | 16 |
1.3. Factors affecting the effects of drugs | 19 |
1.3.1. Body factors | 19 |
1.3.1.1. Breed, species | 19 |
1.3.1.2. Distinction | 20 |
1.3.1.3. Age | 20 |
1.3.1.4. Individual | 21 |
1.3.1.5. Pathological condition | 21 |
1.3.1.6. Routes of drug administration | 22 |
1.3.1.7. Absorption | 22 |
1.3.2. Extra-corporeal factors | 23 |
1.3.2.1. Chemical structure of the drug | 23 |
1.3.2.2. Physical properties of drugs | 23 |
1.3.2.4. Excipients and solvents of the drug | 25 |
1.3.2.5. Other factors | 25 |
1.4. Methods of administering drugs into animals | 26 |
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1.4.1. Transdermal drugs 26
1.4.2. Drugs through the digestive tract 27
1.4.3. Drugs delivered through connective tissue 27
1.5. Transformation and excretion of drugs in the animal body 29
1.5.1. Drug transformation in the body 29
Chapter 2. ANTIBIOTICS AND SULFAMIDES 32
2.1. Antibiotics 33
2.1.1. Concept and classification of antibiotics 33
2.1.1.1. Concept 33
2.1.1.2. Classification 33
2.1.2. Principles of antibiotic combination 33
2.1.2. Principles of antibiotic use 34
2.1.4. Harmful side effects of using antibiotics 34
2.1.5. Some commonly used antibiotics 35
2.1.5.1. Penicillin G 35
2.1.5.2. Streptomycin 36
2.1.5.3. Tylosin 36
2.1.5.4. Gentamicin 37
2.1.5.5. Ampicillin 37
2.1.5.6. MarTylan LA 38
2.1.5.7. Hamolin LA 38
2.2. Sulfamide 39
2.2.1. Definition of Sulfamide 39
2.2.2. Characteristics and mechanism of action of Sulfamide 39
2.2.3. Transformation and excretion of Sulfamide 40
2.2.4. Principles of using sulfonamide 40
2.2.5. Some commonly used Sulfamide drugs 40
2.2.5.1. Sulfaguanidine 40
2.2.5.2. Sulfaquinoxaline 41
2.2.5.3. Sulfachloropyrazine 41
CHAPTER 3: DISINFECTANTS AND ANTI-PARASITICS 43
3.1. Disinfectant 43
3.1.1. ChloramineT 43
3.1.2. Iodine 44
3.1.3. Hantox 200 44
3.1.4. Alcohol 45
3.2.1. Drugs for treating gastrointestinal parasites 46
3.2.1.1. Piperazine 46
3.2.1.2. Mebendazole 47
3.2.1.3. Ivermectin 47
3.2.1.4. Praziquantel 48
3.2.2. Blood parasite treatment drugs 49
3.2.2.1. Berenil 49
3.2.2.2. Naganil- Naganol 50
3.2.2.3. Trypanosoma 50
3.2.3. Drugs for treating skin parasites 51
3.2.3.1. Hantox spray 51
3.2.3.2. Boric acid 52
Chapter 4: DIGESTIVE TREATMENTS AND TONIC 54
4.1. Medicine for horse colic 54
4.1.1. Oral medication 54
4.1.1.1. Magnesium sulfate 54
4.1.1.2. Paraffin 55
4.1.1.3. Pharmalox 56
4.1.2. Injections 56
4.1.2.1. Pilocarpine 56
4.1.2.2. Novocaine 57
4.1.2.3. Diclofenac 2.5% 58
4.1.2.4. Azidine 59
4.2. Supplements 59
4.2.1. Vitamin B1 59
4.2.2. Vitamin C 60
4.2.3. B. complex 61
4.2.4. Vit ADE injection 62
4.2.5. Iron-containing blood tonic 63
4.2.5.1. The role of iron in the animal body 63
4.2.5.2. Fer-Dextran B12 63
4.2.6. Hanlacvet 64
4.2.7. Sodium chloride 0.9% 64
TEXTBOOK FOR VETERINARY PHARMACOLOGY
Subject/module name: Veterinary pharmacology Subject code: MH09
Position, nature, meaning and role of subjects/modules
- Position: Veterinary pharmacology is studied after animal anatomy and physiology. Feed nutrition, Horse selection and breeding.
- Nature: is a basic subject of the industry, belonging to the compulsory subjects.
- Meaning and role of the subject
+ Veterinary pharmacology is a basic subject of veterinary husbandry;
+ After completing the course, students will know the properties and effects of each type of medicine on the animal's body, determine the dosage and how to use the medicines for animals, thereby choosing the medicine and using the appropriate method of delivering the medicine into the animal's body, contributing to improving the effectiveness of treating diseases for animals.
Course objectives:
- About knowledge
+ Present basic contents about concepts, origins, effects, absorption, factors affecting the effects of drugs, routes of drug introduction into the animal body and routes of drug excretion.
+ Describe the properties, effects, uses, and how to use veterinary drugs.
- About skills
+ Identify drug forms, properties, effects, uses and how to use veterinary drugs.
+ Use prescriptions and drugs to treat livestock diseases effectively.
- On autonomy and responsibility:
Ensure safety for people and animals when using drugs for pets.
Course content
Chapter 1: General information about veterinary medicine Chapter 2: Antibiotics and Sulfamides
Chapter 3: Disinfectants and antiparasitics Chapter 4: Gastrointestinal drugs and supplements
Introduce
Chapter I: GENERAL INFORMATION ABOUT VETERINARY MEDICINE
Chapter code: C01
Chapter 1 introduces basic knowledge about veterinary medicine, drug effects, influencing factors, drug administration routes and drug transformation and excretion in the animal body, which is a premise for studying and researching the following chapters.
Target
- Determine the effects of drugs on the animal body
- Point out factors affecting the effects of drugs
- Perform methods of delivering drugs into the animal's body
- Determine the transformation and excretion of drugs in the animal body
- Practice carefulness in studying
Main content
1.1. Concept and origin of veterinary medicine
1.1.1. Concept
1.1.2. Origin of veterinary medicine
1.1.3. Distinguish between drugs, food and poisons
1.2. Effects of the drug
1.2.1. Local and systemic effects
1.2.2. Main effects, side effects
1.2.3. Reflex effect
1.2.4. Remote control effect
1.2.5. Selective and specific effects
1.2.6. Direct and indirect effects
1.2.7. Reversible and irreversible effects
1.2.8. Combined effects
1.3. Factors affecting the effects of drugs
1.3.1. Body factors
1.3.1.1. Breed, species
1.3.1.2. Gender
1.3.1.3. Age
1.3.1.4. Individual
1.3.1.5. Pathological condition
1.3.1.6. Route of administration
1.3.1.7. Absorption
1.3.2. Extra-corporeal factors
1.3.2.1. Drug-related factors
1.3.2.2. Chemical structure of the drug
1.3.2.3. Physical properties of drugs
1.3.2.4. Excipients and solvents of the drug
1.3.2.5. Other factors
1.4. Methods of administering drugs into animals
1.4.1. Transdermal drugs
1.4.2. Drugs administered through the digestive tract
1.4.3. Drugs delivered through connective tissue
1.5. Transformation and excretion of drugs in the animal body
1.5.1. Drug transformation
1.5.2. Drug excretion
1.5.3. Significance of drug excretion transformation





