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APPENDIX 1:

DEFINITION OF GROUPS OF PANCREATIC LYMPH NODES


LOCATION OF LYMPH GROUPS

Source: according to Miyazaki (2015) [1]



Lymph node group Definition


1 Right paracardial lymph node group

2 Left paracardiac lymph node group

3 Groups of lymph nodes along the lesser curvature of the stomach

4 Groups of lymph nodes along the greater curvature of the stomach

5 Suprapyloric lymph nodes


APPENDIX 2


AMERICAN SOCIETY OF ANESTHESIOLOGISTS - ASA HEALTH CLASSIFICATION

(American Society of Anesthesiologists)


ASA 1

Good health

ASA 2

Have a disease that does not affect health and daily life

day.

ASA 3

Have a disease that affects daily activities (diabetes with complications)

vascular disease, obstructive pulmonary disease, angina pectoris…).

ASA 4

Has a serious illness that threatens the patient's life (cancer, heart failure, renal failure)

kidney, abdominal aortic aneurysm, severe bronchial asthma…).

ASA 5

The patient's condition is very serious, dying and unable to live.

24 hours with or without surgery.

ASA 6

Brain dead patient

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APPENDIX 3


TNM CLASSIFICATION ACCORDING TO AJCC – 2010 (Source: AJCC – 2010 [1])

DUODENAL AND VATER'S AMPLE CANCER

T: Tumor size


Tx

Primary tumor not evaluable

T0

No evidence of primary tumor

Tis

Carcinoma in situ

T1

Tumor invades mucosa and submucosa with tumor size ≤ 1 cm

(duodenal cancer); Tumor localized in the sphincter of Oddi (Vater tumor)

T2

Tumor invades the muscle layer or tumor size ≥ 1 cm (duodenal cancer);

Duodenal muscle invasion or tumor size ≥ 1 cm (Vater tumor)

T3

Tumor invades the pancreas and the fat layer around the pancreas

T4

Tumor invades soft tissue around the pancreas or adjacent organs outside the pancreas

N: Regional lymph node metastasis


Nx

No lymph nodes assessed

N0

No regional lymph node metastasis

N1

Regional lymph node metastasis

Regional lymph nodes include groups: 13 (a, b), 17 (a, b), 14 (p, d), 12b, 8 (a, p)

and * 5, * 6 ( * optional)

M: Distant metastasis


Mx

Distant lymph node metastasis cannot be assessed.

M0

No distant metastasis

M1

Distant metastasis

Distant metastasis: lung, bone, pleura, liver, peritoneum, brain, thyroid metastasis

adrenal, non-regional lymph nodes (groups 9, 10, group 16), skin…

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