Malignant Rhabdomyosarcoma (Patient: Pham Van T.)

- Number of tumors: ………..  1 mass  2 - 3 masses  > 3 masses

- Tumor size 1:.................mm  < 5cm  5 – 10 cm  > 10cm

- Tumor size 2:.................mm  < 5cm  5 – 10 cm  > 10cm

- Tumor size 3:.................mm  < 5cm  5 – 10 cm  > 10cm

- Location:  Stomach  Duodenum  Small intestine  Colon  Rectum

 Other locations................................................................................................

- Portal vein thrombosis:  No  Yes  Not described

- Abdominal lymph nodes:  No  Yes  Not described

- Other abnormalities on abdominal ultrasound ...................................................................

D5. Bowel flow imaging:  Do not do

 Can you see the tumor ?  Can you see the tumor?

D6. CT scan:  Do not do

 Can you see the tumor ?  Can you see the tumor?

- CT scan conclusion:

- Ascites:  None  Little  Moderate  Much

- Size: clearly stated..................mm  < 5 cm  5 – 10 cm  > 10cm

- Quantity: clearly state the quantity ………..  1 block  2 - 3 blocks  > 3 blocks

- Location:  Stomach  Duodenum  Small intestine  Colon  Rectum

 Other locations: ...................................................................................................

- Properties on CT:  Increase density  Decrease  Copper  Mixture

 Necrosis...............................  Drug absorption................................

- Portal vein thrombosis:  No  Yes

- Abdominal lymph nodes:  No  Yes

- Other abnormalities:………………..........................................................................

D7. MRI scan:  Do not do

 Can you see the tumor ?  Can you see the tumor?

- MRI scan conclusion:

- Ascites:  None  Little  Moderate  Much

- Size: clearly stated..................mm  < 5 cm  5 – 10 cm  > 10cm

- Quantity: clearly state the quantity ………..  1 block  2 - 3 blocks  > 3 blocks

- Location:  Stomach  Duodenum  Small intestine  Colon  Rectum

 Other locations: ................................................................................................................

- Properties:  Increased signal  Decreased  Same  Mixed

- Portal vein thrombosis:  No  Yes

- Abdominal lymph nodes:  No  Yes

- Other abnormalities:………………..........................................................................

D8. PET-CT:  No  Tumor detected  Tumor detected Description: …………………………………………………………………………….......

D9. Biopsy / CDHA :  No  Yes Result: …..……………………………...

D10. Other surveys (specify):……………………………………………………………….

E. DIAGNOSIS

E1. Preoperative diagnosis: ........................................................................................................

E2. Postoperative diagnosis: .......................................................................................................…………..

F. SURGICAL METHODS  Session  Emergency

PTV :………………………..

F1. Translation :  No  little  medium  much  Not described

F2. Peritoneal metastasis :  Yes  No  Not described F3. Liver metastasis:  Yes  No  Not described F4. Metastasis elsewhere:  Yes ..................................  No

F5. Abdominal lymph nodes:  Yes  No  Not described

F6. Tumor location and corresponding tumor size:

Esophagus:  Upper 1/3......................  Middle 1/3................................  Lower 1/3................................

Stomach:  Cardia.............  Antrum.............  Fundus.................  Pylorus ................

 BCL...................  BCN...................................

 Duodenum: D ........... .....................

 Jejunum .....................  Ileum ...........................

Colon:  Cecum..........  Ascending colon............  Transverse colon............  Descending colon............

 Singma phone...............  Right phone................  Left phone................

 Rectum ..........  Anus .......... Other locations :..........................................................

F7. Color:  Pinkish white / yellowish white  Pinkish brown, gray

F8. Type of surgery:

 Laparoscopic Surgery  Open Surgery  Laparoscopic Conversion to Open  Endoscopic Assistance

 Biopsy exploration  Open or bypass (cannot remove tumor)

 Wedge resection  Local tumor resection (through the anus or rectum)

 Cut the OH with tumor:  Immediately repeat digestion  Take it out for HMNT.  Amputate the TT

 1 position  2 positions  3 positions  4 positions  5 positions

Specifically:  Esophagus  Stomach  Duodenum  Jejunum  Ileum  Cecum

 Upward phone  Horizontal phone  Downward phone  Singma phone  Right phone  Left phone

 Rectum  Anus  Other: ............................................................................

F9. Lymph node dissection:  Yes  No

F10. Other: …………........................................................................................................

................................................................................................................................................................ G. PATHOLOGY: Number: ……………… ICD-10: ………….. ICD-0: …… GROSS IMAGE

G1. Number of tumors: (specify the number of tumors) ………………………………………………....

Classification of tumor number  1 tumor  2 – 3 tumors  > 3 tumors

G2. Location and corresponding tumor size (mm):

Esophagus:  Upper 1/3......................  Middle 1/3................................  Lower.................................

Stomach:  Cardia.............  Fundus.............  Antrum.............  Pylorus .................

 BCL...................  BCN...................................

 Duodenum: D(1-4) ........... .....................

 Jejunum .....................  Ileum ...........................

Colon:  Ascending colon...........  Transverse colon............  Descending colon............  Singma colon..............

 Right phone................  Left phone................

 Rectum ...............  Anus .................... Location

other:.........................................

G3. Tumor density:  Firm  Soft  Mixed  Not described

G4. Tumor shape:  Sphere, mass, polyp, lobule  Flat, plaque, infiltrating  Not described G5. Capsule, border:  Yes  No/Diffuse infiltration  Not described G6. Tumor color:  Pinkish white / yellowish white  Pinkish reddish brown, gray  Not described MICROSCOPE RESULTS

G7. Definitive diagnosis (cytological diagnosis)

 Lymphoma  Leiomyoma  Rhabdomyosarcoma  GIST  Granuloma  Lipoma

 Hemangioma  Melanoma  Schwannoma  Kaposi sarcoma  Glomus tumor

Suspect: …………………………………………………………………………………...

IMMUNOHYTOCHEMISTRY

G8. Immunohistochemistry:  To be done  Not required  If positive, required, but not yet done Marker Type: ......................................................................................................................

Result: ............................................................................................................................

G9. Suspected differential diagnosis: .....................................................................................

H. POSTOPERATIVE FOLLOW-UP

H1 . General results:  Death, severe  Good discharged from hospital

H2. Reoperation  No  Yes: (due to: …………………………)

H3 . Early complications:  No  Yes

 Surgical site infection  Pleural effusion  Residual abscess  Peritonitis

 Urinary tract infection  Anastomotic leak  Pneumonia  Postoperative bleeding

 Multiple organ failure  Urinary retention

H4. Long-term follow-up (assessment at the end of the study)

 Died Date: ......../......../.............

 Living with disease recurrence

 Live without disease

Recording method:  Telephone interview. Date of call:...................../Meeting:..................... Postoperative adjuvant treatment:  No  Yes

 Chemotherapy  Radiotherapy  Chemoradiotherapy  Targeted therapy  Immunotherapy Other: …………………………………………………………………………….....

Survival time after surgery: …………(months)

Appendix 2

MICROPHOTOGRAPHY AND IMMUNOCHYTOCHEMISTRY

07 TYPES OF NON-EPHELIAL CARCINOMA

1. Malignant rhabdomyosarcoma (Patient: Pham Van T.)


HE x 100: Spindle-shaped tumor cells, arranged bundle	HE x 400: Cytoplasm of tumor cells is pink, large nucleus, clear nucleolus, many mitotic divisions

DESMIN: Cytoplasmic positive tumor cells	MYOGLOBIN: Granular positive with tumor cell cytoplasm

SMA: Negative for tumor cells	DOG 1: Negative for tumor cells

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2. Liposarcoma (Patient: Pham Trong C.)

HE x 100: Highly differentiated tumor component with

tumor cells have wide vacuoles, nuclei at the edge of the cytoplasm

HE x 100: Anaplastic tumor component with spindle-shaped tumor cells and oval nuclei

HE x 100: Anaplastic tumor component

with spindle-shaped tumor cells, oval nuclei

HE x 400: Rich in mitotic figures

3. Angiosarcoma (Patient: Nguyen Van M.)

HE x 100: Epithelioid tumor cells,

interspersed with blood vessels

HE x 100: Epithelioid tumor cells,

interspersed with blood vessels

HE x 100: Epithelioid tumor cells,

interspersed with blood vessels

HE x 400: Clear nucleus, distorted nuclear membrane,

rich in division

HE x 400: Clear nucleus, distorted nuclear membrane

rich, multiplied

HE x 400: Clear nucleus, distorted nuclear membrane,

rich in division

4. Gastrointestinal stromal tumor (GIST) (Patient: Nguyen Thi L.)


HE x 100: Spindle cell tumor with oval nucleus, bundle	HE x 400: Spindle-shaped tumor cells, oval nucleus arrange into bundles

DOG1: Strongly positive for nucleus and cytoplasm	CD117: Cytoplasmic positive

S100: Negative for tumor cells, positive calculated with internal evidence.	SMA: Negative for tumor cells, positive calculated with internal evidence.

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