Some characteristics and risk factors of hearing loss in children from 2 to 5 years old in inner-city kindergartens in Hanoi - 1


MINISTRY OF EDUCATION AND TRAINING MINISTRY OF HEALTH CENTRAL INSTITUTE OF HYGIENE AND EPIDEMIOLOGY


NGUYEN TUYET XUONG

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SOME CHARACTERISTICS AND RISK FACTORS OF HEARING LOSS IN CHILDREN FROM 2 TO 5 YEARS OLD AT KINDERGARTENS IN HANOI CITY

Some characteristics and risk factors of hearing loss in children from 2 to 5 years old in inner-city kindergartens in Hanoi - 1


Major: Epidemiology Code: 62.72.01.17


DOCTORAL THESIS IN EPIDEMIOLOGY


Scientific instructor:


1. Associate Professor, Dr. Nguyen Anh Dung


2. Associate Professor, Dr. Khu Thi Khanh Dung


HANOI – 2014


COMMITMENT


I hereby declare that this thesis is my own research work, conducted by myself. The data is collected seriously and honestly. The results in the thesis have never been published in any other work.


PhD student


INDEX

ABBREVIATIONS v

LIST OF TABLES

LIST OF FIGURES AND DIAGRAMS viii

PROBLEM STATEMENT 1

CHAPTER 1 DOCUMENT OVERVIEW 3

1.1. Anatomy and physiology of the auditory system 3

1.1.1. Brief anatomy of the ear [90] 3

1.1.2. Hearing physiology [24] 5

1.2. Auditory testing methods 6

1.2.1. Ear examination 6

1.2.2. Audiological tests 6

1.2.3. Auditory testing methods used in Vietnam 13

1.3. Classification and degree of hearing loss 15

1.3.1. Classification of hearing loss 15

1.3.2. Hearing loss level 16

1.4.Hearing loss situation 18

1.4.1. Hearing loss situation in the world 18

1.4.2. Hearing loss situation in Vietnam 21

1.5. Risk factors for hearing loss in children 23

1.5.1. Congenital factors 23

1.5.2. Causes of acquisition 27

1.6. Effects of hearing loss 30

1.7. Hearing loss interventions 31

1.7.1. Hearing aids 31

1.7.2. Language recovery methods 32

CHAPTER 2 RESEARCH SUBJECTS AND METHODS 33

2.1 Research subjects 33

2.2 Research location 33

2.3 Research time 34

2.4 Research design 34

2.5 Sample size and sample selection 34

2.6 Data collection method 36

2.7 Data collection tools 38

2.8 Research indicators and variables 40

2.9 Correcting error 44

2.10 Data management and processing 44

2.11 Ethics in Research 45

2.12 Some limitations and limitations of the study 45

CHAPTER 3 RESULTS 47

3.1. Characteristics of hearing loss in preschool children from 2 to 5 years old 47

3.1.1 General information about the research subjects 47

3.1.2 Results of the first otoacoustic emission measurement (OAE) in the community 48

3.1.3 Characteristics of hearing loss in Hanoi inner-city preschool children through ABR or monophonic measurement 51

3.2 Analysis of risk factors for hearing loss in children from 2 to 5 years old 62

3.2.1 Some characteristics of the research subjects 62

3.2.2 Identify risk factors for hearing loss 63

CHAPTER 4 DISCUSSION 70

4.1. Characteristics of hearing loss in preschool children in inner-city Hanoi 70

4.1.1 Characteristics of research subjects 70

4.1.2 Prevalence of hearing loss through screening using the OAE 71 method

4.1.3 Prevalence of hearing loss measured by OAE by age 75

4.1.4 Prevalence of hearing loss measured by OAE by gender 76

4.1.5 Hearing loss by ear location 77

4.1.6 Hearing loss level in preschool children in inner-city Hanoi 77

4.1.7 Forms of hearing loss in preschool children in inner-city Hanoi 79

4.2. Risk factors for hearing loss in preschool children from 2-5 years old in inner-city Hanoi 80

4.2.1. Prenatal factors 80

4.2.2. Factors during birth 82

4.2.3. Postnatal factors 87

CONCLUSION 91

1. Characteristics of hearing loss in preschool children in public preschools in Hanoi in 2011 - 2012 91

2. Some risk factors of hearing loss in children from 2 to 5 years old in Hanoi inner city 91

RECOMMENDATION 92

PUBLISHED WORKS ............................................................................

REFERENCES..........................................................................................


ABR Auditory Brainstem Response‌

ASL American Sign Language – American Sign Language

ASHA American Speech - Language-Hearing Association - American Speech - Language - Hearing Association

CI Cochlear implantation - Cochlear implantation

Hib Haemophilus influenzae type b

OAE Otoacoustic Emission - Otoacoustic Emission

OAE(-) Negative cochlear stimulation

OAE(+) Positive otoacoustic stimulation

OR Odd Ratio - Odds Ratio

World Health Organization World Health Organization

ENT

Expanded Immunization Program

VTG Otitis media

Chronic otitis media

VTTD Otitis media with effusion

VXC Mastoiditis

VMN Meningitis

VMNM Purulent meningitis


Table 1.1: Hearing loss levels according to ASHA [60] 16‌

Table 1.2: Hearing loss levels according to the World Health Organization [62] 16

Table 1.3: Classification of hearing loss in infants in some studies in Vietnam[12] 17

Table 1.4: Classification of hearing loss levels currently used at the National Children's Hospital..17

Table 2.1: List of schools and number of children aged 2 to 5 years participating in hearing loss screening 36

Table 2.2: Classification of hearing loss levels 40

Table 2.3: Definition of research variables 41

Table 3.1: Distribution of study subjects by district (n=7,191) 47

Table 3.2: Distribution of study subjects by age (n=7,191) 48

Table 3.3: OAE rate (-) by district (n=7,191) 48

Table 3.4: Results of the second OAE measurement of children with OAE (-) the first time (n=337) 50

Table 3.5: Prevalence of hearing loss by district (n=7191) 51

Table 3.6: Characteristics of hearing loss by age and gender (n=314) 53

Table 3.7: Characteristics of children with hearing loss by ear location and gender (n=314) 53

Table 3.8: Results of tympanometry examination for children with hearing loss 54

Table 3.9: Results of the stapedial reflex in hearing-impaired children 55

Table 3.10: Hearing loss level of children by gender (n=314) 56

Table 3.11. Level of hearing loss in children by age 56

Table 3.12: Forms of hearing loss by gender (n = 314) 57

Table 3.13: Forms of hearing loss by age (n = 314) 58

Table 3.14: Characteristics of maternal medical history during pregnancy of hearing-impaired children (n = 314) 59

Table 3.15: Birth history characteristics of children with hearing loss (n=314) 60

Table 3.16: Characteristics of medical history of children with hearing loss (n=314) 61

Table 3.17: Age distribution of study subjects (n=942) 62

Table 3.18: Characteristics of study subjects by gender (n=942) 62

Table 3.19: Association between maternal history of illness during pregnancy and risk of hearing loss in children 63

Table 3.20: Association between birth history and risk of hearing loss in children .. 65 Table 3.21: Association between postnatal factors and risk of hearing loss in children

................................................................ ................................................................ ................ 67

Table 3.22: Association between prenatal, intranatal and postnatal factors with hearing loss in children - multivariate regression analysis model, Model 1 68

Table 3.23: Association between prenatal, intranatal and postnatal factors with hearing loss in children - multivariate regression analysis model, Model 2 69

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